Undecylenoyl Phenylalanine, Sepiwhite MSH(CAS 175357-18-3)
Product Name: Undecylenoyl Phenylalanine
Alias: Sepiwhite MSH, N-Undecylenoyl-L-Phenylalanine
INCI Name: Undecylenoyl Phenylalanine
CAS No.: 175357-18-3
Grade: Cosmetic Premium Grade (High-Efficiency Whitening & Spot Fading)
Purity: ≥99.0%
Appearance: White to Off-White Fine Crystalline Powder, Uniform Texture, No Impurities, Odorless
Molecular Formula: C₂₀H₂₉NO₃
Molecular Weight: 331.45
MOQ (Minimum Order Quantity): 25KG
Solubility: Slightly soluble in water, easily soluble in ethanol, glycerin and polar cosmetic solvents; good dispersion in aqueous and emulsion systems, stable compatibility with common whitening active ingredients
Core Efficacy: Block melanin synthesis signal, inhibit melanin proliferation, fade pigmentation and spots, brighten dull skin tone, even skin texture, prevent tanning and color sinking
Key Characteristics: Biomimetic α-MSH antagonistic structure, multi-stage melanin inhibition, ultra-low concentration efficacy, mild non-irritating, no photosensitivity, synergistic whitening with nicotinamide, long-term brightening and anti-suntan effect
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; strictly sealed after opening to prevent moisture absorption and agglomeration
Shelf Life: 24 Months
Application: Widely used in whitening serum, brightening facial cream, spot fading essence, anti-tanning lotion, facial mask, emulsion and high-end skin brightening functional skin care formulas
Undecylenoyl Phenylalanine, Sepiwhite MSH, Cosmetic Grade Undecylenoyl Phenylalanine, Anti-melanin Agent, Skin Whitening Brightener, Freckle Removing Ingredient, Skin Color Evenning Raw Material
Undecylenoyl Phenylalanine, Sepiwhite MSH(CAS 175357-18-3)
Cosmetic Grade Undecylenoyl Phenylalanine (Sepiwhite MSH) is a high-efficiency biomimetic whitening and spot-fading active ingredient, specially developed for professional skin brightening and anti-pigmentation skincare. Different from traditional whitening ingredients that only inhibit tyrosinase, it adopts innovative α-MSH signal antagonism technology.
It achieves multi-stage whole-process inhibition of melanin generation, with stable and long-lasting whitening effect, effectively improving dull yellow skin, sun tan, freckles and uneven skin tone.
The product features ultra-high activity, obvious efficacy at low concentration, mild and skin-friendly properties, no irritation, no photosensitivity, and can be used day and night.
It has excellent synergistic effect when compounded with nicotinamide, VC derivatives and other whitening ingredients, which can greatly improve the comprehensive brightening effect and avoid whitening bottlenecks.
With stable chemical properties, good system compatibility and no impact on formula color and fragrance, it is a core high-end active raw material for safe and efficient whitening skincare.



Key Benefits
• Source Signal Blocking, Whole-process Anti-melanin: Different from single tyrosinase inhibition, it blocks melanin synthesis signal at the source, suppresses melanocyte activity in advance, prevents pigment precipitation fundamentally, and solves dullness and tanning more thoroughly.
• Low Dosage & High Efficiency, Outstanding Efficacy: Ultra-high biomimetic activity, significant whitening effect at ultra-low concentration, low addition cost, high cost performance, suitable for high-end lightweight whitening formulas.
• Mild & Non-photosensitive, Day & Night Available: Non-irritating and non-sensitizing, no photosensitive risk, no need to avoid light, safe for long-term use on sensitive skin, breaks the limitation of traditional whitening ingredients only for night use.
• Strong Synergistic Effect, Break Whitening Bottleneck: Perfectly compatible with nicotinamide, VC, arbutin and other whitening actives, multi-dimensional synergistic whitening, layer-by-layer fading spots and pigmentation, significantly improve brightening effect.
• Improve Uneven Skin Tone & Fade Old Pigment: Effectively improve sun tan, hormonal spots, dull yellow and uneven skin tone, lighten old pigment precipitation, restore transparent and uniform skin texture.
• Stable Formula & Wide Compatibility: Excellent acid-base stability, not easy to deactivate and discolor, good solubility and dispersion in water and emulsion systems, convenient for industrial production and formula debugging.
Applications
• High-Efficiency Whitening Serum & Essence: Core active ingredient of brightening essence, spot-fading stock solution and anti-tanning serum, achieve source melanin inhibition and rapid skin brightening.
• Brightening Facial Cream & Lotion: Added in whitening face cream, moisturizing lotion and daily brightening skincare products, long-term uniform skin tone, improve dull yellow and dry dark skin.
• Spot Fading & Repair Skin Care Products: Suitable for targeted spot-fading creams, pigment repair products, improve sunburn pigmentation, acne marks and local color unevenness.
• Anti-Tanning & Post-Sun Repair Formulas: Used in pre-sun protection and post-sun repair products, inhibit UV-induced melanin proliferation, prevent tanning and fix sun darkening skin.
• Whitening Facial Mask & Functional Skincare: Added in brightening facial masks and concentrated whitening formulas, quickly improve facial dullness, make skin transparent and bright in a short time.
• Mild Sensitive Skin Whitening Products: As a mild high-efficiency whitening active, replace irritating whitening ingredients, build safe and gentle brightening skincare system for sensitive skin.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Undecylenoyl Phenylalanine | Compliant |
CAS No. | 175357-18-3 | Compliant |
Appearance | White to Off-White Fine Powder | Compliant |
Purity | ≥99.0% | 99.63% |
Melting Point | 118℃~125℃ | 121.4℃ |
Loss on Drying | ≤0.5% | 0.12% |
Residue on Ignition | ≤0.1% | 0.03% |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Microorganism | ≤100CFU/g, No Pathogenic Bacteria | Qualified |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Undecylenoyl Phenylalanine?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and whitening efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 0.5%-2.0% for whitening essence and cream; 0.2%-1.0% for daily brightening lotion and mask, adjustable according to pigment fading and brightening requirements.
• Q4: Why is it better than traditional whitening ingredients?
A4: It acts on the upstream melanin signal pathway, inhibits melanin from the source, no photosensitivity, can be used day and night, and has more lasting and stable whitening effect than single tyrosinase inhibitors.
• Q5: Can it be compounded with nicotinamide?
A5: Yes, the compound system of Undecylenoyl Phenylalanine and nicotinamide forms a dual anti-melanin mechanism of "source blocking + transport inhibition", which greatly enhances whitening and spot-fading effect.
• Q6: Is it suitable for sensitive skin whitening products?
A6: The product is highly purified, mild and non-irritating, non-sensitizing, no burden on the skin barrier, fully suitable for sensitive skin long-term brightening maintenance.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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